MRSA induced pulmonary-renal syndrome

It is no secret that the link between infection and vasculitis is well established even though the exact mechanism is still under study [1]. Infection, in addition to other factors, has been counted to trigger Vasculitis. The causal relationship has been documented only in few cases like Polyarthritis Nodosa (PNA)/Hepatitis B virus (HBV) and Cryoglobulinemia/Hepatitis C virus (HCV) cases [1]. There has also been an established link between MethicillinResistant-Staphylococcus aureus (MRSA) and Microscopic Polyangitis with perinuclear anti-neutrophils-cytoplasmic-antibody (PANCA) [2]. In addition, post MRSA infection IgA glomerulonephritis [2] is well described. We present a rare case of pulmonary-renal syndrome secondary to recurrent MRSA spondylodiscitis. The mechanism of involvement of each organ system is unique. The organs, lung and kidneys, have been affected by different pathologic processes that were induced, we think, by the chronic MRSA infection.